World Alliance of Societies of Echocardiography (WASE) Normal Values Study


Do normal chamber quantification values vary across countries, geographical regions, and cultures? That is the question ASE plans to answer, with the help of ASE International Alliance Partners and friends. The World Alliance of Societies of Echocardiography (WASE) Normal Values Study has organized study centers in six continents, including the US, Canada, Mexico, Brazil, Argentina, Australia, Nigeria, India, China, Japan, Korea, Philippines, Iran, Italy, and the United Kingdom.

Principal Investigators for the overall study are Roberto M. Lang, MD, FASE and Federico M. Asch, MD, FASE. “We believe the information derived from this effort will be of benefit for echocardiography worldwide, not only in describing each population but in comparing them to each other,” said Dr. Lang.

The WASE study, which was launched at ASE 2016 during a meeting with the Investigators for each study center, will entail the acquisition of complete 2D and 3D echocardiograms in 100 individuals of both genders and across a wide range of ages in each of 15 countries. All echoes will be analyzed in collaboration with MedStar Health Research Institute and the University of Chicago. The clinical usefulness of echocardiography is based on the detection of abnormalities, which relies on the accurate definition of “normality” across different countries or races. Currently, available echocardiographic “reference values” that define “normality” are mostly based on cross-sectional observations of Caucasians from the US and Europe.

In addition to Drs. Lang and Asch, the current Steering Committee for this study is comprised of Jose Banchs, MD, FASE; Vera Rigolin, MD, FASE; James D. Thomas, MD, FASE; Neil J. Weissman, MD, FASE; and Susan Wiegers, MD, FASE.

The WASE Normal Values Study is being funded by the American Society of Echocardiography Foundation and its donors, and with generous in-kind support from sponsors TOMTEC Imaging Systems, Medidata, Medstar Health Research Institute, and University of Chicago.

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